Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity Reporting into the Vice President, Commercial Operations, the Senior Director, Commercial Training & Development is a highly visible, enterprise-level leadership role responsible for defining and driving all training needs to support U.S. commercialization and global expansion. Senior Director will serve as the strategic owner of the training and readiness function of our customer-facing teams (field and/or home office). We anticipate hiring the Senior Director, Commercial Training & Development in September 2026 Responsibilities * Design and implement a flexible customer engagement training model that supports multiple field-based teams and serves as the scalable foundation for ongoing training needs across the commercial organization * Build comprehensive and compelling training curricula across disease state, product, customer engagement, launch readiness, compliance, and role-specific competencies (e.g., manage care organization / field reimbursement account teams, patient services teams, thought leader liaison teams, sales management) for a rare endocrine condition or similarly specialized therapeutic area * Manage external training vendors and agency partners to develop high-quality, scientifically accurate, compliant, and engaging training content aligned to commercial strategy and field execution needs * Partner seamlessly with Sales, Marketing, Medical Affairs, Market Access, Patient Services, Compliance, and other field leaders to ensure training content is strategically aligned, medically accurate, compliant, operationally relevant, and reflects the authentic experience of our HCP and community stakeholders * Partner with analytics teams to measure the impact of training curricula and implementation * Manage meeting/planning vendor resources for all field meetings, including product launch meetings, field POA meetings, annual NSM, etc. * Experience establishing training infrastructure, processes, governance, measurement approaches, and continuous improvement practices to support a 2027 product launch and future commercial growth Required Qualifications * Bachelor’s degree required * 12+ years of experience in pharmaceutical or biotech customer-facing training, with increasing levels of responsibility * Significant experience and success leading customer-facing commercial training and development teams, ideally in rare disease, specialty, or complex launch environments * Strong understanding of how to translate brand strategy, medical insights, market access priorities, and customer needs into practical training programs that improve field readiness and customer engagement effectiveness * Exceptional communication and executive presence * Strong vendor management, budget oversight, and project management skills Preferred Qualifications * Advanced degree (PhD, MD, PharmD, or MBA)    Work Location and Conditions * At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee. * Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis. * If outside of the New England region, you will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation. * When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.   Compensation The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Estimated Pay Range $248,000—$279,000 USD To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn. To return to our website please click here. Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.